The POLYSYS modeling framework enables detailed assessment of agricultural biomass resources herbaceous, intermediate and short rotation woody crops, at the county level, with sub-county downscaling via interaction with the Cropland Data Layer. It provides estimates of biomass availability aligned with agricultural markets, incorporating potential impacts of significant land use changes. Additionally, POLYSYS offers stochastic modeling for probability estimates on resource levels and prices. This multifaceted approach aids stakeholders in analyzing policy, economic changes, and resource conditions for biomass initiatives, offering insights into crop supply, livestock demand, and agricultural income. Its scenario analysis capabilities allow exploration of various input prices, land-use patterns, and environmental constraints, ensuring sustainability. POLYSYS also considers community economic impacts, providing a holistic understanding of biomass project influences. Long-term projections aid strategic planning, customizable to regional goals. Integration with supply chain models optimizes processing facility location, feed costs, equipment, and storage, identifying needs for supporting the supply chain’s viability.